After one-to-one propensity score matching, 21 patients were included in the local infiltration analgesia group and 21 in the genicular nerve block group. We conducted propensity score-matched analyses of patients using acute postoperative pain-related risk covariates. The pain numeric rating scale and the cumulative opioid consumption in oral morphine equivalents during the first 24 h. Genicular nerve blocks in the prospective cohort were compared with local infiltration analgesia in the retrospective cohort. Thirty-five patients scheduled for total knee arthroplasty were prospectively included in the study and compared with 35 patients in a retrospective cohort. To test the noninferiority of the analgesic effect of genicular nerves block in comparison with local infiltration analgesia after 24 h of total knee arthroplasty. Blockade and radiofrequency ablation of the genicular nerves are effective treatments for patients with chronic pain because of knee osteoarthritis. Standard analgesic strategies for total knee arthroplasty employ local infiltration analgesia.
Future trials are required to investigate the incremental benefits provided by local anesthetic infiltration between the popliteal artery and the capsule of the knee (IPACK), popliteal plexus block and genicular nerve block.
The optimal analgesic strategy for TKR may include a combination of different analgesic modalities (periarticular infiltration, femoral triangle blocks, obturator nerve block). Combined femoral triangle-obturator blocks result in improved analgesia and swifter discharge compared with femoral triangle blocks alone. However, these benefits seem less pronounced when perineural adjuvants are used. Continuous femoral triangle blocks provide superior postoperative analgesia compared with their single-injection counterparts. When combined with the latter, femoral triangle blocks are associated with improved pain control, higher patient satisfaction and decreased opioid consumption. The cumulative evidence suggests that femoral triangle blocks outperform placebo and periarticular infiltration.
#Escaner con contraste riesgos registration
Randomized controlled trials lacking prospective registration and blinded assessment were excluded. Only trials including motor-sparing interventions were included.
MEDLINE, EMBASE and CINAHL databases were searched (inception-last week of May 2020). Pharmacokinetics, safety and efficacy of a new gadolinium-based contrast agent, P03277, in pediatric patients from 2 to 17 years of age undergoing central nervous system contrast-enhanced MRI.This scoping review investigates the optimal combination of motor-sparing analgesic interventions for patients undergoing total knee replacement (TKR). Proof of Concept study concerning efficacy of P03277 MR Imaging in HCC diagnosis Phase IIa Clinical Study Étude de preuve de concept relative à l’efficacité du P03277 dans l’imagerie par résonance. P03277 Dose Finding Study in Central Nervous System (CNS) Magnetic Resonance Imaging (MRI) Studio di ricerca della dose di P03277 in risonanze magnetiche per immagini (Magnetic Resonance Imaging, M. Xenetix 350 : Evaluación comparativa de la calidad de imagen en la angiografía de las arterias coronarias mediante escáner Xenetix 350 : comparative assessment of image quality for coronary CT angiog.ĭiagnostic contribution of XENETIX® CT PERFUSION in pre-therapeutical assessment of hepatocellular carcinoma.ĭOTAREM® Pharmacokinetics, Safety and Efficacy Study in Pediatric Subjects Aged <2 Years (Term Newborn Infants to Toddlers 23 Months of Age Inclusive) DOTAREM® Studie zur Pharmakokinetik, Sicherhei. Intra-individual efficacy evaluation of DOTAREM®-enhanced MRA compared to GADOVIST®–enhanced MRA in the diagnosis of clinically significant abdominal or limb arterial diseasesĮvaluación de la seguridad y la eficacia de Dotarem en resonancia magnética (RM) en pacientes con lesiones del sistema nervioso central (SNC) SAFETY AND EFFICACY EVALUATION OF DOTAREM® IN MAGNETIC RE. Listed as ongoing, but also has a completion dateĪ RANDOMIZED DOUBLE-BLIND PARALLELL GROUP CLINICAL STUDY OF XENETIX 300 VERSUS VISIPAQUE 270 IN MULTISLICE CT PEDIATRIC INDICATIONSĬomparison of the diagnostic efficacy of Xenetix 350 and Iomeron 400, for visualisation of the aorta and abdominal vascular tree with 64-slices computed tomographyĮVALUACIÓN DE LA SEGURIDAD RENAL TRAS ARM POTENCIADA CON DOTAREM EN COMPARACIÓN CON LA RM SIN CONTRASTE ENTRE PACIENTES CON ALTO RIESGO DE PADECER NEFROPATIA PROVOCADA POR EL MEDIO DE CONTRASTE RENA.Įfficacy evaluation of DOTAREM-enhanced MRA compared to GADOVIST-enhanced MRA in the diagnosis of clinical significant abdominal or lower limb arterial diseases These trials have problematic data on the registry.
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